Nausea and upset stomach may occur. If either of these effects persists or worsens, tell your doctor or pharmacist promptly.
When not to use
Hypersensitivity to the drug and patients with Diabetic ketoacidosis and Impaired kidney function
Full Prescribing Info
Contents
Glimepiride.
Description
However, metabolites serum levels (mean AUC values) increased. The apparent terminal t½ for glimepiride did not change, while the half-lives for metabolites increased as renal function decreased. Mean urinary excretion of metabolites as percent of dose, however, decreased.
Indications/Uses
Dosage/Direction for Use
Usual Starting Dose: 1-2 mg once daily, administered with breakfast or the 1st main meal The maximum starting dose of glimepiride should not be >2 mg.
Usual Maintenance Dose: 1-4 mg once daily. The maximum recommended dose is 8 mg once daily. After reaching a dose of 2 mg, dose increases should be made in increments of >2 mg at 1-2 week intervals based upon the patient’s blood glucose response
Recommended Getryl Dose: 8 mg once daily administered with the 1st main meal.
Special Populations: In elderly, debilitated or malnourished patients, or in patients with hepatic insufficiency, the initial dosing, dose increments and maintenance dosage should be conservative to avoid hypoglycemic reactions.
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